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Benign Prostatic hypertrophy
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The most common prostate condition is BPH (benign prostatic hypertrophy)  In Europe approximately 75% of men over 50 develop symptoms of BPH 

What is BPH (benign prostatic hypertrophy)?

  • BPH is a non-malignant (non-cancerous) enlargement of the prostate gland - a common occurrence in older men.

  • It is caused by an overgrowth of prostate cells. This enlargement constricts the urethra so the flow of urine is reduced, making it increasingly difficult to empty the bladder.

  • BPH generally begins in a man's 30's, evolves slowly and usually only causes symptoms after 50.

  • Although BPH is an extremely common condition, only 10 per cent of men need medical or surgical intervention. It is not a precursor to prostate cancer.

 

Why are older men vulnerable to BPH?  

As men get older, there is a surplus in the amount of testosterone produced by the testicles. This excess is absorbed by  the prostate.  

Testosterone can convert to dihydrotestosterone which causes an increase in the growth of prostate cells and the lifespan of these cells. The result is growth of the prostate. Since the prostate surrounds the urethra, this growth slowly begins to put pressure on the urethra as it exits the bladder. Over time the pressure can cause obstruction and reduce the flow of urine from the bladder.  

Symptoms

  • Hesitancy (difficulty in starting to pass urine)

  • A weak stream

  • The need to strain to pass urine

  • The feeling that the bladder isn't empty after urination

  • The need to pass urine urgently

  • Dribbling, being unable to completely stop the flow of urine

  • Frequent trips to the toilet, including having to get up several times in the night

  • Feeling a burning sensation or pain when passing urine

Treatments  

Talk to your doctor about the various remedies and treatments available. For mild cases, many doctors recommend Saw Palmetto, a herbal remedy, widely regarded as useful in reducing size of the prostate, though not everyone responds. Some products combine saw palmetto with nettle and other ingredients – see our product of the month below.

While the most widely used conventional treatment for BPH has been surgical intervention, in recent years pharmaceuticals that inhibit the conversion of testosterone to DHT have been increasingly prescribed. The most common surgical method to shrink the prostate is transurethral resection of the prostate (TURP) where part of the gland is removed. This usually involves a few nights in hospital, some weeks of recovery and possible side effects including impotence. Not a method to be undertaken lightly.

Newest for severe cases is laser treatment, which involves light  pulsing on the prostate to reduce obstruction, carried out in a day clinic. But few hospitals in the UK can offer this at the moment. Many doctors prefer to suggest herbal treatments as a first option.    

 

PRODUCT OF THE MONTH - December 2003  

Saw Palmetto Complex  

Saw Palmetto Complex is a special formula comprised of standardized extracts of saw palmetto, pygeum africanum and stinging nettle, all thought to be useful for treating BPH and improving impaired bladder functions. Some studies show that ingredients may even help shrink and normalize the prostate, safely.  

Saw Palmetto Complex contains, per capsule: 

Saw Palmetto (Serenoa repens) extract (berry) 107mg

Stinging Nettle (Urtica dioica) extract (leaf) 100mg

Beta-sitosterol 100mg

Pygeum (Prunus africanum) extract (bark) 33mg

Lycopene 5mg

Recommended dosage: one capsule, three times daily with meals    

Saw Palmetto is a plant extract derived from a palm. It is known as a phytochemical and many trials using Standardised Extract of Saw Palmetto have  been shown to help improve symptoms of BPH. 

It doesn't affect prostate-specific antigen levels (PSA) a test used for indication of prostate cancer. Commonly prescribed drugs for BPH have been found to significantly lower PSA levels, and this may mask the ability of PSA tests to detect cancer. A twice-daily dose of 160 milligrams has shown improvement within 60 days.

Pygeum comes from a tree growing in parts of Africa . Recent research with standardized Pygeum Africanum Extract (PAE) suggests that it contains several types of phytochemicals thought to be useful for treating BPH. Most studies have used 75 to 200 milligrams daily in one or two doses, with improvement within two months.

Lycopene is a tomato-based product that may help in preventing prostate cancer.  It  is considered a powerful antioxidant, and its inclusion in Saw Palmetto Complex is thought to be a useful preventative.

Beta-Sitosterol: one of the phytosterols produced naturally  by plants and found in corn and soy oil. It is considered by many researchers as a useful treatment with encouraging results in trials.

Stinging Nettle has a diuretic effect, to help make passing urine easier.

Nutricentre2.jpg (19300 bytes)

Saw Palmetto Complex  costs £38.95 for 90 capsules and is available on line from the Nutri Centre (Code VRP 1620) and health food stores and chemists.

 

Useful contacts

For all-round information about prostate conditions, join the  Prostate Help Association. It’s a self-help group run by one dedicated man, Philip Dunn who has recently come under criticism for appearing to work as a charity, but without charitable status. In fact, this was stated in his newsletter where Dunn said being a charity caused too much bureaucracy for a lone organiser.    

Dunn single-handedly produces a quarterly newsletter ‘Prostate Focus’. An indigested read, it nevertheless is full of information, patient-oriented, and keeps very up-to-date on treatments and research.  

Also available is a publications list and 2000 pages of prostate information on CDs. See the website: http://www.pha.u-net.com or email: philip@pha.u-net.com. 

For general information about men’s health, see the free website www.malehealth.co.uk, which is run by the Men’s Health Forum, commended in the BMA’s 2003 Patient Information Awards.   

The site is aimed at males of all ages. At its heart is a Health A-Z section which covers 24 common health topics in a clear Q and A format. It includes the Male Body - A User’s Guide, an overview of every part of the male anatomy for beginners. There’s an instant online health report and a home MOT health check, frank advice on lifestyle and information on men’s favourite subjects: drink, smoking, sex, food and exercise. There is even an online gym with a fitness programme


Meanwhile, we thank the publication What Doctors Don’t Tell You  for the following:  

PSA: It's a test that has had its day  We (WDDTY) have said it before, and now we have to say it again-the prostate specific antigen (PSA) blood test doesn't work. In fact, it works less well than even we thought.  A new study has found that it's failing to recognize eight out of every 10 cases of prostate cancer.

Researchers from Harvard Medical School analysed the test results of 6,691 men who had a PSA, and found that it failed to spot 82 per cent of cancer cases. The test also came up with just 2 per cent of 'false positives' - where the test detected a cancer that wasn't actually there - a pretty low rating compared to most other tests that throw up many more false positives.

So what can be done? The test currently assesses as healthy a PSA blood concentration of 4 ng/ml. If this was reduced to 2.6 ng/ml, researchers reckon that the test would detect around 36 per cent of cancers - but it would also dramatically increase the rate of false positives.  This is still not an acceptable detection rate. It's perhaps time to discard the PSA and search for a more reliable test.


(Source: New England Journal of Medicine, 2003; 349: 335-42).


 

laterlife interest

The above article is part of the features section of laterlife.com called laterlife interest. laterlife interest contains a variety of articles of interest for visitors to laterlife.com written by a number of experienced and new journalists.

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